Key result
Treatment with paroxetine or fluvoxamine induced galactorrhea and hyperprolactinemia in three female patients, which completely resolved upon discontinuation of the medications.
Why the study?
Galactorrhea with antidepressants was infrequent, with previously reported cases mostly involving combined antidepressants and normal serum prolactin levels with paroxetine and fluvoxamine.
Population
Three cases of galactorrhea in nonpregnant women of child-bearing age
Comparison
Single use of paroxetine or fluvoxamine
Design
Case series
Authors
Loading...
Raises awareness for galactorrhea with paroxetine or fluvoxamine; hypothesis-generating and should not yet change practice.
Case Report (n=3)
Paroxetine and fluvoxamine can induce galactorrhea with hyperprolactinemia, which resolves upon discontinuation of the medication.
Bhattacharjee et al. (2021) conducted a case report in SSRI-induced galactorrhea with hyperprolactinemia (n=3). SSRIs (paroxetine and fluvoxamine) was evaluated on Development of galactorrhea and elevated serum prolactin levels. Treatment with paroxetine or fluvoxamine induced galactorrhea and hyperprolactinemia in three female patients, which completely resolved upon discontinuation of the medications.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: