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AMBINON1 is a commercial gonadotropic extract obtained from the anterior lobe of pituitary glands. The sterile solution is standardized to contain a gonadotropic potency of 50 rat units and thyrotropic potency of 200 guinea pig units per milliliter. Preliminary investigations at this station have shown that the response resulting from the injection of gonadotropic hormones of direct pituitary origin is quite different from the action of the gonad-stimulating properties present in pregnant-mare serum. Since the response of the ovarian follicles of the bird occurred readily when Ambinon was injected, it was thought that the egg production of hens and pullets might be improved by supplementing the normal hormone content of the body. Differences in methods of preparation and administration of the hormone extracts may account for the variable results reported by Walker (1925), Noether (1928 Noether (1930), Dubowik (1930), and Renoult (1931). Now it appears that even inter-hen variability resulting from . . .
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R. E. Phillips (1943) studied this question.
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