Why the study?
Does vaccination with specific IBV strains improve viral clearance in chickens challenged with avian infectious bronchitis virus?
Population
Chickens (model for avian infectious bronchitis virus)
Comparison
Vaccination with 20 PD50 of one of 4 vaccinating… vs Unvaccinated chickens
Design
Preclinical
Follow-up
3 weeks post-vaccination, then 4 days post-challenge
Authors
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May advance D41 as broad-spectrum IBV vaccine candidate in poultry; leaves open field validation.
Does vaccination with specific IBV strains improve viral clearance in chickens challenged with avian infectious bronchitis virus?
The D41 strain demonstrates broad-spectrum protection against multiple strains of avian infectious bronchitis virus in a chicken clearance model.
J.H. Darbyshire (1985) studied this question.
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