Key result
Dogs with chronic congestive heart failure exhibited a procoagulant state with significantly higher fibrinogen, D-dimer, and TAT concentrations compared to healthy controls.
Authors
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May support thromboprophylaxis consideration in canine CHF; hypothesis-generating for prospective trials.
Case-Control (n=57)
Yes
Tarnow et al. (2007) conducted a case-control in Chronic congestive heart failure (CHF) (n=57). Chronic congestive heart failure vs. Healthy age-matched control dogs was evaluated on Plasma concentration or activity of hemostatic biomarkers and mortality. Dogs with chronic congestive heart failure exhibited a procoagulant state with significantly higher fibrinogen, D-dimer, and TAT concentrations compared to healthy controls.
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