What question did this study set out to answer?

To assess the in vitro antimicrobial susceptibility profiles of clinical Nocardia species isolates against 20 antimicrobial agents.

March 15, 2011Antimicrobial Agents and ChemotherapyOpen Access

Susceptibility of 186 Nocardia sp. Isolates to 20 Antimicrobial Agents

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Authors

JLJulián LarruskainBiogipuzkoa Health Research Institute PIPedro IdígorasUniversity of the Basque Country JMJosé María MarimónBiogipuzkoa Health Research Institute

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Implication

Observational study reveals complete susceptibility to linezolid and amikacin in clinical Nocardia isolates, highlighting effective therapies against resistant strains.

Key Points

To assess the in vitro antimicrobial susceptibility profiles of clinical Nocardia species isolates against 20 antimicrobial agents.
Evaluated 186 clinical isolates of Nocardia spp. collected in Gipuzkoa, northern Spain, between 1998 and 2009.
Identified bacterial species and specimen sources, predominantly respiratory tract samples.
Tested in vitro susceptibility against a panel of 20 antimicrobial agents.
The most prevalent species were Nocardia nova, N. farcinica, N. cyriacigeorgica, N. abscessus, and N. carnea.
All 186 isolates (100%) were susceptible to linezolid and amikacin.
A majority of N. flavorosea, N. carnea, and N. farcinica isolates exhibited resistance to trimethoprim-sulfamethoxazole.

Cite This Study

Larruskain et al. (2011) studied this question.

synapsesocial.com/papers/6a918d7204fde5146cafa727 https://doi.org/10.1128/aac.01279-10

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Implication

Observational study reveals complete susceptibility to linezolid and amikacin in clinical Nocardia isolates, highlighting effective therapies against resistant strains.

Susceptibility of 186 Nocardia sp. Isolates to 20 Antimicrobial Agents

Discussion

Member takes

Implication

Key Points

Cite This Study

Susceptibility of 186 Nocardia sp. Isolates to 20 Antimicrobial Agents

Discussion

Member takes

Implication

Key Points

Cite This Study

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