Key result
Hepatic resection significantly increased postoperative prothrombin times compared to preoperative values, with prolongation related to surgery duration and resection weight.
Why the study?
Does hepatic resection alter prothrombin time in the postoperative period in patients with normal preoperative coagulation?
Cohort (n=124)
No
Does hepatic resection alter prothrombin time in the postoperative period in patients with normal preoperative coagulation?
Hepatic resection significantly prolongs prothrombin time postoperatively even in patients with normal baseline coagulation, which should be considered when planning epidural analgesia.
No takes yet. Share an insight, caveat, or question.
May warrant caution with neuraxial techniques after hepatic resection; leaves open need for prospective validation in patients with normal baseline coagulation.
Weinberg et al. (2006) conducted a cohort in Hepatic resection (n=124). Hepatic resection vs. Preoperative values was evaluated on Prothrombin time. Hepatic resection significantly increased postoperative prothrombin times compared to preoperative values, with prolongation related to surgery duration and resection weight.
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