June 1, 2025Advances in Patient-Reported OutcomesOpen Access
Crosswalk between PROMIS computer adaptive tests and numerical rating scales in cancer patients: Anxiety, depression, pain interference, physical function
Key result
Numerical rating scales (NRS) and PROMIS CAT scores were strongly correlated (0.72-0.78) across four symptom domains in cancer patients, enabling the creation of a conversion crosswalk.
Why the study?
The study aimed to establish a crosswalk between PROMIS computer adaptive tests and numerical rating scales for anxiety, depression, pain interference, and physical function.
Population
34,029 unique patients from the E2C2 trial
Comparison
0-10 numerical rating scales linked to PROMIS CAT scores
Design
Retrospective analysis using single-group equipercentile linking
Authors
Discussion
Loading...
Member takes
Implication
May enable PRO integration across scales in symptom care; leaves open prospective validation before routine use.
Study Design
Type
Observational (n=34,029)
Structured PICO
P
Population
34,029 cancer patients (median age 64, 56% female) from a pragmatic symptom management trial who completed both NRS and PROMIS CAT assessments.
O
Outcome
Crosswalk between PROMIS computer adaptive tests (CATs) and numerical rating scales (NRS) in emotional distress-anxiety, emotional distress-depression, pain interference, and physical functionpatient reported
Main Result
Effect estimate: Correlation 0.72-0.78
This study provides a crosswalk table to convert 0-10 numerical rating scales into PROMIS CAT T-scores for cancer patients, facilitating the interpretability of symptom scores.
Cite This Study
Lee et al. (2025) conducted an observational in Cancer (n=34,029). Numerical rating scales (NRS) vs. PROMIS computer adaptive tests (CATs) was evaluated on Correlation between NRS and PROMIS scores (Correlation 0.72-0.78). Numerical rating scales (NRS) and PROMIS CAT scores were strongly correlated (0.72-0.78) across four symptom domains in cancer patients, enabling the creation of a conversion crosswalk.