Key result
End-stage renal disease patients exhibited significantly lower preoperative heart rate variability compared to healthy donors (SDNN 29.3 vs 47.6 ms), which declined further in the early post-transplant period.
Why the study?
While kidney transplantation may restore physiological homeostasis, its short-term impact on heart rate variability remains unclear.
Does kidney transplantation alter short-term heart rate variability in patients with end-stage renal disease compared to healthy donors?
Observational (n=61)
No
Does kidney transplantation alter short-term heart rate variability in patients with end-stage renal disease compared to healthy donors?
Patients with end-stage renal disease have significantly impaired preoperative heart rate variability compared to healthy donors, reflecting baseline autonomic dysfunction.
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Çamkıran et al. (2025) conducted an observational in End-stage renal disease (ESRD) (n=61). End-stage renal disease / Kidney transplantation vs. Healthy living donors was evaluated on Preoperative standard deviation of the normal-to-normal intervals (SDNN) (p=<0.001). End-stage renal disease patients exhibited significantly lower preoperative heart rate variability compared to healthy donors (SDNN 29.3 vs 47.6 ms), which declined further in the early post-transplant period.
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