Why the study?
Does cisapride therapy at 0.8 mg/kg per day prolong the corrected QT interval in premature infants and children?
Population
30 premature infants in a neonatal intensive care unit and children seen at a pediatric gastroenterology…
Comparison
Cisapride 0.8 mg/kg per day for 1 month vs Baseline or after cessation of therapy
Design
Cohort
Follow-up
1 month
Authors
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Supports QT safety of cisapride 0.8 mg/kg/day in low-risk infants; hypothesis-generating pending randomized confirmation.
Does cisapride therapy at 0.8 mg/kg per day prolong the corrected QT interval in premature infants and children?
Cisapride at 0.8 mg/kg per day does not appear to significantly prolong the corrected QT interval in premature infants and children without other risk factors.
Levine et al. (1998) studied this question.
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