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June 7, 2004Journal of Asian Natural Products Research

Shikonin regulates H e L a cell death via caspase-3 activation and blockage of DNA synthesis

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Authors

ZWZhen WuWLWU Li-junLLLinhao Li

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Wu et al. (2004) studied this question.

synapsesocial.com/papers/6a91adb9cd6b16172ebe496ehttps://doi.org/10.1080/1028602032000169622
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  1. 1Antitumor activity of shikonin, alkannin and their derivatives. II. X-ray analysis of cyclo-alkannin leucoacetate, tautomerism of alkannin and cyclo-alkannin and antitumor activity of alkannin derivatives.1981 · 53 citations
  2. 2Phosphorylated Forms of Activated Caspases Are Present in Cytosol From HL-60 Cells During Etoposide-Induced Apoptosis1998 · 45 citations
  3. 3The Mutagenic Constituents of Rubia tinctorum.1992 · 322 citations
  4. 4Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikonin1992 · 147 citations
  5. 5Caspase-3 Is the Primary Activator of Apoptotic DNA Fragmentation via DNA Fragmentation Factor-45/Inhibitor of Caspase-activated DNase Inactivation1999 · 486 citations