Why the study?
Do desflurane, sevoflurane, and propofol have different effects on QT, QTc, and P dispersion on ECG in patients undergoing noncardiac surgery?
Population
46 patients from the American Society of Anesthesiologists class I-II undergoing noncardiac surgery
Comparison
Desflurane, sevoflurane, or propofol anesthesia vs Active comparators and baseline
Design
RCT, randomly allocated, double-blinded
Follow-up
5 minutes after drug administration
Authors
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Desflurane increases QT/P dispersion while propofol decreases QTc dispersion; extends RCT evidence guiding anesthetic choice in arrhythmia-prone patients.
Do desflurane, sevoflurane, and propofol have different effects on QT, QTc, and P dispersion on ECG in patients undergoing noncardiac surgery?
Desflurane increases QT and P dispersion compared to sevoflurane and propofol, suggesting a potential need for caution in patients with high arrhythmia risk.
Kazancı et al. (2009) studied this question.
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