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During the course of a recent study of certain mucoproteins in serum (1, 2) we became interested in the general properties of the electrophoresis pattern of serum at pH 4.5. It was felt that the electrophoresis pattern at pH 4.5 might be of some value in the study of pathological sera in other re- spects than as a means of demonstrating changes in mucoprotein. The present paper is concerned primarily with the comparison between the electrophoresis patterns of various samples of pathological sera at pH 8.5 and pH 4.5.
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Mehl et al. (1950) studied this question.
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