Macrophage activation syndrome should be considered as a potential infrequent complication in patients with Kawasaki disease and prolonged fever.
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Alerts clinicians to macrophage activation syndrome risk in Kawasaki disease with prolonged fever; leaves open its incidence and management implications.
Kawasaki disease (KD) patients are known to be at increased risk for coronary artery lesions. We present evidence of another possible complication associated with KD: macrophage activation syndrome (MAS). In this case, a patient with KD and prolonged fever developed MAS. This case is of particular interest because of the late age of onset and recurrent nature of KD as well as the complication of MAS. We also present a review of the literature that supports the inclusion of MAS as an infrequent complication of KD.
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Muise et al. (2003) studied this question.
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