Mass spectrometric quantification of polychlorinated biphenyl congeners using multiple carbon-13 internal standards

Multiple carbon-13 internal standards improve the precision and accuracy of the mass spectrometric analysis of polychlorinatedbiphenyl (PCB) congeners compared to analyses using a single carbon-13 internal standard. The mean percentage error in PCB congener analysis on the μg g−1 level using multiple ion detection and three carbon-13 internal standards was 6.29%. This precision in single laboratory work suggests that the method will be useful for interlaboratory studies monitoring PCB residues and contaminats of public health significance.