Answers are grounded in this paper and cite their sources.
Splitless and on-column injectors were evaluated for use in quantitative multi-residue analysis of priority micropollutants by wall-coated open-tubular gas chromatography. Under limited conditions some splitless injectors yield quantitative results. However, on-column injection devices have a broader range of applicability and yield better precision and accuracy. For quantitation of wide boiling range mixtures, such as polychlorinated biphenyls, at picogram levels, on-column injection devices are the only ones which yield satisfactory results.
No takes yet. Share an insight, caveat, or question.
Onuska et al. (1983) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: