Why the study?
What are the differences in clinical profile, management, and outcomes between patients with out-of-hospital cardiac arrest with and without STEMI?
What are the differences in clinical profile, management, and outcomes between patients with out-of-hospital cardiac arrest with and without STEMI?
In patients with out-of-hospital cardiac arrest, those with STEMI have a distinct clinical profile (younger, more often male smokers with fewer comorbidities) and have experienced improved survival and increased use of reperfusion therapies over time.
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Distinct OHCA+STEMI profiles may inform initial triage; leaves open whether rising thrombolysis improves survival.
AIM OF THE STUDY: We studied the clinical profile, management, and outcomes of patients with out-of-hospital cardiac arrest (OHCA) with and without ST-elevation myocardial infarction (STEMI). METHODS: Retrospective analysis of the 20-year registry data (January 1991- June 2010) was conducted on patients with cardiac disease hospitalized at Hamad General Hospital and Qatar Heart Hospital, Doha, Qatar. RESULTS: A total of 987 patients with OHCA were admitted to the cardiology department during the study period; among them, 296 (30%) patients had STEMI. Compared to the patients with OHCA without STEMI, the patients who had OHCA with STEMI were younger (53 ± 13 vs 58 ± 16 years; P = .001), more likely to be male (78% vs 34%; P = .001), smokers (35% vs 14%) but less likely to have hypertension (30% vs 48%; P = .001), diabetes (32% vs 47%, P = .001), and chronic renal failure (3.4% vs 9%; P = .002). The use of thrombolytic treatment in patients with STEMI increased from 21.6% (period 1991-1095) to 44.4% (period 2006-2010); P = .04. CONCLUSION: Percutaneous coronary intervention had increased significantly during the last quarter of the study. There was a decline in the in-hospital mortality among patients with STEMI during the last quarter of the study.
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Arabi et al. (2017) studied this question.
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