Chronic Zinc Deficiency Syndrome in a Beer Drinker With a Billroth Ii Resection

A 51-year-old woman, addicted to beer for several years, developed chronic zinc deficiency which caused severe mental impairment, a poor general condition with edema and diarrhea, widespread eczema craquelé and loss of hair. Laboratory tests showed a significantly lowered serum zinc concentration, microcytic anemia, an inversed serum albumin/gamma-globulin ratio and a decreased serum thyroxine. Two years earlier, her external pancreatic function had been found severely impaired. Following oral therapy with zinc sulfate 0.2 g X 3R, daily, the patient's mental and physical condition totally changed. In two weeks serum zinc was within the normal range, while hemoglobin concentration, serum proteins, serum thyroxine became normal in 4-8 weeks.