Why the study?
Does low-dose clonidine cause cardiac dysrhythmia in a child without preexisting cardiac disease?
Does low-dose clonidine cause cardiac dysrhythmia in a child without preexisting cardiac disease?
Low-dose clonidine can induce bradycardia and irregular sinoatrial node firing even in children without preexisting cardiac disease.
May warrant heart rate monitoring with low-dose clonidine in children; case report leaves open causality and generalizability.
Clonidine has been used in the management of hypertension in adults with few cases of cardiac dysrhythmia reported. These appear to occur most frequently in association with preexisting cardiac disease or toxic concentrations of the drug. We observed a case of clonidine-induced bradycardia and irregular firing of the sinoatrial node in a child who does not have cardiac disease given low doses of the drug in the treatment of intermittent explosive disorder.
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Dawson et al. (1989) studied this question.
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