Drugs and the Embryo

MEDICLNpatients was their unprompted admission that on this drug they felt generally better than previously.In my limited experience of this new hypo- tensive agent it would appear to be a potent and useful drug for the common types of hypertension.Individual dose requirements appear to be wide but considerably lower than found by Peart and MacMahon.The critical dose level is narrow and it should be administered cautiously, starting with 5 mg.b.d. and increasing the dose by 5 mg.b.d.every three to seven days until a satisfactory response is reached.The value of the drug is enhanced by its satisfactory hypotensive effect on the lying as well as the standing blood-pressure in all cases studied.-Iam, etc.,