Macrocyclic Gadolinium-Based Contrast Agents Do Not Cause Hyperintensity in the Dentate Nucleus

We wish to comment on the December 2015 article of Ramalho et al[1][1] entitled “Gadolinium-Based Contrast Agent Accumulation and Toxicity: An Update” in the American Journal of Neuroradiology . First, the authors introduced the study of Stojanov et al,[2][2] in which gadobutrol (Gadavist;