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December 1, 1994Journal of Clinical InvestigationOpen Access

Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.

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KMKeishi MakitaOji General HospitalKTKentaro TakahashiSUNY Upstate Medical UniversityAKArmando KararaUniversity of Buenos Aires

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Cite This Study

Makita et al. (1994) studied this question.

synapsesocial.com/papers/6a92575d2b0d7d237a435f82https://doi.org/10.1172/jci117608
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Also Consider

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  1. 1Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney1991 · 72 citations
  2. 2A Genetic Polymorphism in the Renin Gene of Dahl Rats Cosegregates with Blood Pressure1989 · 294 citations
  3. 3Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid.1981 · 295 citations
  4. 4Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo1990 · 1,864 citations
  5. 5Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading.1992 · 147 citations