Primary Hyperparathyroidism Associated with Hypomagnesemia

CONCLUSIVE evidence of a clinical syndrome related to a deficiency of magnesium in man is lacking. We have had the opportunity recently to observe 3 patients who, in the course of adenomatous hyperparathyroidism proved by surgical exploration, demonstrated clinical abnormalities believed to be related to magnesium deficiency. A preliminary report has been published.1 MethodsThe serum and urine magnesium concentrations of Cases 1 and 3 were determined by the method of Briggs.2 With duplicate aliquots of serum and urine, calcium was precipitated as calcium oxalate, and from aliquots of the supernatant magnesium was precipitated as magnesium ammonium phosphate. A slight . . .