3-3-1 Formation: [Pd(PPh3)4]/CuI serves as an efficient catalyst for the reaction of three readily available starting materials to give 3-(diarylmethylene)indolin-2-ones 3 through a sequence of intermolecular Sonagashira reaction/intermolecular carbopalladation/CH activation/CC bond formation (see scheme). Three CC bonds are thereby formed as a result of three distinct catalytic cycles with one catalyst. DMF=N,N-dimethylformamide.
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Pinto et al. (2007) studied this question.
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