that into Golgi and can be largely explained by uptake into Golgi-like lipoprotein-containing vesicles.The data are compatible with the view that processing of internalized insulin begins in Golgi.Chloroquine inhibits this initial processing step, leading to accumulation of internalized hormone in lipoprotein-containing Golgi vesicles.
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Posner et al. (1982) studied this question.
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