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tein.These peptides, which originated from the region surrounding the single tryptophan residue, contain the major encephalitogenic determinant of the Al protein (9, lo), a unique polypeptide sequence of no more than 9 residues (Peptide T27) :Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gin-Lys * The amino acid analysis was carried out with the Beckman autoanalyzer following 24-hour hydrolysis in 6 N HCl at 110'.The Val-Val sequence is only partially hydrolyzed under these conditions (21).
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Eylar et al. (1971) studied this question.
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