Oral Ketoconazole and Intraocular Amphotericin B for Treatment of Postoperative Candida parapsilosis Endophthalmitis

To the Editor. —PostoperativeCandida parapsilosisendophthalmitis occurred in a group of patients secondary to the administration of a contaminated lot of intraocular irrigating solution. All patients underwent subsequent therapeutic vitrectomy combined with intravitreal amphotericin B, intravenous intraocular amphotericin B, and oral flucytosine therapy; this group of 15 patients has previously been described.1We recently treated an additional patient who was exposed to the same lot of contaminated irrigating solution and had a prolonged delay in the presentation of postoperativeC parapsilosisendophthalmitis. Report of a Case. —An 89-year-old healthy man underwent extracapsular cataract extraction with implantation of an anterior chamber intraocular lens in the right eye in July 1983. Postoperatively, he had a mild persistent iridocyclitis that was treated intermittently with a topical corticosteroid over the ensuing two years. Two months before our examination, the patient noted a mild increase in redness in the eye that had been