Why the study?
Does admission to a tertiary paediatric intensive care unit compared to general intensive care units improve survival in critically ill children?
Does admission to a tertiary paediatric intensive care unit compared to general intensive care units improve survival in critically ill children?
Critically ill children with a high predicted mortality risk (≥30%) have better survival in tertiary pediatric intensive care units compared to general intensive care units.
May warrant consideration of tertiary PICU transfer for highest-risk cases; leaves open whether unmeasured confounding explains the association.
AIMS: To evaluate the performance of the Paediatric Risk of Mortality (PRISM) score in a population of UK children and to use this score to examine severity of illness adjusted mortality of critically ill children <16 years old in a defined geographical region. METHODS: Observational study of a defined population of critically ill children (<16 years old) admitted to hospitals in the South West Region between 1 December 1996 and 30 November 1998. RESULTS: Data were collected from 1148 eligible admissions. PRISM was found to perform acceptably in this population. There was no significant difference between the overall number of observed deaths and those predicted by PRISM. Admissions with mortality risk 30% or greater had significantly greater odds ratio for death in general intensive care units compared with the tertiary paediatric intensive care unit. CONCLUSIONS: Children with a high initial risk of mortality based on PRISM score were significantly more likely to survive in a tertiary paediatric intensive care unit than in general intensive care units in this region. However, there was no evidence from this study that admissions with lower mortality risk than 30% had significantly worse mortality in non-tertiary general units than in tertiary paediatric intensive care units.
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A. John Henderson (2002) studied this question.
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