Injectable Poly-L-Lactic Acid (PLLA): Practical Approaches to Optimize Outcomes

The use of injectable devices for soft-tissue augmentation has been associated with the occurrence of adverse events. The present case report discusses the successful treatment and resolution of painful nodules that were histologically shown to be foreign body granulomas in a patient who had previously received injectable poly-L-lactic acid for the correction of nasolabial folds, the neck, and zygomatic area. Incorrect injection placement and method may have led to the formation of granulomatous nodules. Properly trained professionals can minimize or avoid the occurrence of many of these types of adverse events for their patients by employing proper reconstitution and injection techniques and injecting appropriate/indicated areas. If granulomas do occur, full resolution may be expected following a course of triamcinolone injections.