Why the study?
Does the presence of diabetes mellitus and/or chronic kidney disease increase the risk of acute coronary syndrome in a population-based cohort?
Population
957,867 patients without a history of acute coronary syndrome before 2000, derived from the Taiwan National…
Comparison
Presence of diabetes mellitus and/or chronic… vs Absence of diabetes mellitus and chronic kidney…
Design
Cohort
Follow-up
2000 to 2007
Authors
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DM may warrant prioritized ACS risk assessment over CKD alone in adults <45; extends multiplicative interaction data but remains hypothesis-generating.
Does the presence of diabetes mellitus and/or chronic kidney disease increase the risk of acute coronary syndrome in a population-based cohort?
Diabetes mellitus and chronic kidney disease confer different levels of acute coronary syndrome risk depending on age, sex, and other cardiovascular risk factors, with DM posing a higher risk than CKD in younger patients.
Chang et al. (2014) studied this question.
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