Why the study?
Placental insufficiency is a serious condition in pregnancy that can cause complications, and low molecular weight heparin is a potential treatment.
Does low molecular weight heparin improve outcomes in pregnant females presenting with placental insufficiency?
Does low molecular weight heparin improve outcomes in pregnant females presenting with placental insufficiency?
In pregnant females with placental insufficiency, treatment with LMWH resulted in preterm delivery in 26.9% and SGA in 8% of cases.
Answers are grounded in this paper and cite their sources.
May warrant LMWH consideration in placental insufficiency; leaves open need for randomized confirmation before practice change.
Introduction: Placental insufficiency is a serious condition that affects pregnant women and can lead to a range of complications during pregnancy. One potential treatment for this condition is the use of low molecular weight heparin. Objectives: The main objective of the study is to assess the outcome of low molecular weight heparin for management of females presenting with placental insufficiency. Material and methods: This descriptive case series was conducted in Unit II, Department of Obstetrics & Gynecology, Lady Willingdon Hospital, Lahore. Sample size of 175 cases was calculated with 95% confidence level, 4.5% margin of error and taking expected percentage of SGA i.e. 10.1% with LMWH in females placental insufficiency. Data was collected through non-probability consecutive sampling technique. Results: In this present study total 175 females were enrolled. The mean age of the females was 29.70±6.36 years with minimum and maximum ages of 20 & 40 years respectively. In this study the mean gestational age of the females was 33.99±1.43 weeks with minimum and maximum values of 32 & 36 weeks respectively. 35(20%) females had null parity, 37(21.14%) females had primary, 45(25.71%) females had secondary parity and rest of the females belonged to multiple parity. Practical implication: This study will be helpful in finding outcome by LMWH for management of females presenting with placental insufficiency Conclusion: According to this study the outcome by LMWH for management of females presenting with placental insufficiency showed preterm delivery in 26.9% and SGA in 8% females.
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Nisar et al. (2023) studied this question.
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