Why the study?
Do endovascular methods for closure of the left atrial appendage prevent thromboembolic events in patients with nonvalvular atrial fibrillation compared to long-term anticoagulant therapy?
Do endovascular methods for closure of the left atrial appendage prevent thromboembolic events in patients with nonvalvular atrial fibrillation compared to long-term anticoagulant therapy?
This review summarizes the evidence, advantages, and design features of various left atrial appendage occlusion devices as an alternative to long-term anticoagulation for stroke prevention in nonvalvular atrial fibrillation.
LAA occlusion devices may offer anticoagulation alternative in nonvalvular AF; leaves open need for randomized confirmation of safety and efficacy.
The paper presents an update on endovascular methods for closure of the left atrial appendage in order to prevent thromboembolic events in patients with nonvalvular atrial fibrillation. It analyzes the results of occlusion devices as an alternative to longterm anticoagulant therapy from the standpoint of evidencebased medicine, advantages, and features of design and implantation of occlusion devices, such as Watchman, Amplatzer, WaveCrest, and Lariat system. Literature searching was carried out using the databases PubMed and Scopus.
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Guchaev et al. (2018) studied this question.
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