Cancer risk and mortality in users of calcium channel blockers
Why the study?
Does the use of calcium channel blockers increase cancer incidence or mortality in a population-based cohort?
Population
23,167 users of calcium channel blockers who received >=2 prescriptions between January 1, 1989 and December…
Comparison
Calcium channel blockers (>=2 prescriptions) vs Background population (expected rates)
Design
Cohort
Authors
Discussion
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Member takes
Implication
No excess cancer risk seen with calcium channel blockers; extends observational safety data but leaves randomized confirmation open.
Structured PICO
Does the use of calcium channel blockers increase cancer incidence or mortality in a population-based cohort?
P
Population
23,167 users of calcium channel blockers who received >=2 prescriptions between January 1, 1989 and December 31, 1995 in North Jutland County, Denmark.
I
Intervention
Calcium channel blockers (>=2 prescriptions)
C
Comparator
Background population (expected rates)
O
Outcome
Cancer incidence and cancer mortalitysafety
The use of calcium channel blockers is not associated with an increased risk of cancer incidence or cancer mortality.
Cite This Study
Sørensen et al. (2000) studied this question.