Why the study?
Does ropivacaine 0.125% reduce hourly dose requirement compared to bupivacaine 0.125% in parturients receiving epidural analgesia during labour?
Does ropivacaine 0.125% reduce hourly dose requirement compared to bupivacaine 0.125% in parturients receiving epidural analgesia during labour?
Ropivacaine 0.125% and bupivacaine 0.125% are equally effective when self-administered for epidural analgesia during labour.
In this randomised, controlled study, we compared the hourly dose requirement of ropivacaine 0.125% (group R, n = 16) with bupivacaine 0.125% (group B, n = 16) provided by demand‐only (bolus 5 ml, lockout 10 min) parturient‐controlled epidural analgesia during labour. The hourly dose requirement was comparable although group R had a lower successful to total demands ratio (p < 0.05). We also found that both groups were clinically indistinguishable in terms of pain relief and side‐effects. No difference in maternal or fetal outcome was detected. We conclude that, at a concentration of 0.125%, ropivacaine and bupivacaine were equally effective when self‐administered using this patient‐controlled regimen.
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Chua et al. (2001) studied this question.
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