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The design of two-dyed fluorescent silica nanoparticles for ATP detection is presented. The indicator dye possesses a dipicolyl-amine (DPA) unit complexed with Zn(II) as a receptor function for ATP while a rhodamine derivative is used as the reference dye. The nanoparticles were fully characterized regarding analytical performance, morphology and cytocompatibility.
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Moro et al. (2011) studied this question.
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