The Use of Latex Fixation Tests in Non-rheumatic States

Article1 October 1963The Use of Latex Fixation Tests in Non-rheumatic StatesHUBERT I. CAPLAN, M.D.HUBERT I. CAPLAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-59-4-449 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA number of serologic procedures have been developed in recent years in the search for a diagnostic test for rheumatoid arthritis, for example, latex fixation tests. None of these have proved to be highly sensitive and, at the same time, specific for rheumatoid arthritis. This is not surprising since the very factors tested are generally nonspecific macroglobulins. In addition, until its cause and pathogenesis are known, rheumatoid arthritis cannot be defined precisely.The use of latex fixation tests in other medical problems has received little attention. It is the purpose of this report to describe some of these uses in...References1. SINGERPLOTZ JMCM: Slide latex fixation test. JAMA 168: 180, 1958. CrossrefMedlineGoogle Scholar2. CAPLAN HI: Evaluation of the eosin slide latex fixation test for rheumatoid arthritis. Bull. Tufts New Eng. Med. Cent. 6: 136, 1960. MedlineGoogle Scholar3. LANEDECKER JJJC: Latex particle tests in rheumatoid arthritis. JAMA 173: 980, 1960. CrossrefGoogle Scholar4. DRESNERTROMBLY EP: The latex-fixation reaction in non rheumatic diseases. New Eng. J. Med. 261: 981, 1959. CrossrefMedlineGoogle Scholar5. HOWELLMALCOLMPHE DSJMR: The FII agglutinating factors in serums of patients with non-rheumatic diseases. Amer. J. Med. 29: 662, 1960. CrossrefMedlineGoogle Scholar6. KUNKELSIMONFUDENBERG HGHJH: Observations concerning positive serologic reactions for rheumatoid factor in certain patients with sarcoidosis and other hyperglobulinemic states. Arthritis Rheum. 1: 289, 1958. CrossrefMedlineGoogle Scholar7. BARTFELD H: Immunologic and biologic similarities of seropositive rheumatoid and non rheumatoid disease sera: gel diffusion studies. J. Lab. Clin. Med. 56: 303, 1960. MedlineGoogle Scholar8. BONOMOLO SPALLUTOZIFF LJM: Antigamma globulin factors in liver disease. Arthritis Rheum. 6: 104, 1963. CrossrefMedlineGoogle Scholar9. ATWATERJACOX ECRF: The latex-fixation test in patients with liver disease. Ann. Intern. Med. 58: 419, 1963. LinkGoogle Scholar10. BARTFELD H: Incidence and significance of seropositive tests for rheumatoid factor in non-rheumatoid disease. Ann. Intern. Med. 52: 1059, 1960. LinkGoogle Scholar11. ALSEVER JB: The blood donor. II. Blood donors associated with serum hepatitis; an analysis of 211 donors involved in 70 cases. Amer. J. Med. Sci. 240: 48, 1960. CrossrefGoogle Scholar12. PELTIERCHRISTIAN ACL: The presence of the rheumatoid factor in sera from patients with syphilis. Arthritis Rheum. 2: 1, 1959. CrossrefMedlineGoogle Scholar13. KRITZMANKUNKELMCCARTHYMELLORS JHGJRC: Studies of a Waldenström-type macroglobulin with rheumatoid factor properties. J. Lab. Clin. Med. 57: 905, 1961. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, MassachusettsFrom the Department of Medicine and the Rheumatic Disease Unit of the Tufts—New England Medical Center, Boston, Massachusetts.Presented at the Forty-third Annual Session of the American College of Physicians, Philadelphia, Pennsylvania, April 9-13, 1962.Requests for reprints should be addressed to Hubert I. Caplan, M.D., 185 Harrison Avenue, Boston, Massachusetts. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThe Association between Autoimmunity and Agnogenic Myeloid MetaplasiaLatex agglutination test for detection of Australia antigen (HB-Ag) among blood donors and patientsLatex-Fixation Test to Screen Blood DonorsCirrhosis of the liver in Iran a prospective study on 66 casesPreoperative Preparation of the Jaundiced Patient: A Review of Current PracticePeriarticular inflammation, bilateral hilar adenopathy and a sarcoid reactionDie ErythrocytenCOMPLEMENT-FIXING LIVER ANTIBODIES.Latex Slide Test in Thyroid DiseasesA Genetic Approach to the Pathogenesis of Hepatic Cirrhosis A Clinical and Serological StudyTissue-Specific AntigensDRUGS AND DRIVINGHYALURONIDASE IN CARPAL TUNNEL SYNDROMELATEX-FIXATION TEST IN THE RETICULOSES 1 October 1963Volume 59, Issue 4Page: 449-454KeywordsCirrhosisHepatitis A virusInflammationLatexMyelomaPathogenesisPatientsProteinsRheumatoid arthritis Issue Published: 1 October 1963 PDF DownloadLoading ...