Why the study?
An optimal strategy for left atrial ablation in addition to pulmonary vein isolation (PVI) in patients with persistent atrial fibrillation had not been determined.
Does additional left atrial ablation after pulmonary vein isolation reduce the recurrence of atrial fibrillation or atrial tachycardia in patients with persistent atrial fibrillation?
Population
Patients with persistent AF (n=248 in PVI-alone, n=248 in PVI-plus)
Comparison
PVI-plus strategy vs PVI-alone strategy
Design
Extended follow-up of a multicenter randomized controlled trial
Follow-up
3 years after enrollment
Authors
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Additional ablation beyond PVI may lower 3-year recurrence in persistent AF; leaves open optimal lesion sets and iatrogenic AT risks.
Does additional left atrial ablation after pulmonary vein isolation reduce the recurrence of atrial fibrillation or atrial tachycardia in patients with persistent atrial fibrillation?
Additional left atrial ablation, specifically linear ablation, after PVI reduces long-term AF/AT recurrence in persistent AF but may increase the risk of iatrogenic atrial tachycardias.
Masuda et al. (2023) studied this question.