Why the study?
Does 67Ga imaging accurately detect clinically suspected head and neck tumors and lymphoma compared to pathological findings?
Does 67Ga imaging accurately detect clinically suspected head and neck tumors and lymphoma compared to pathological findings?
67Ga imaging has moderate accuracy for head and neck tumors and high accuracy for lymphoma, being particularly valuable for detecting intraabdominal lymphoma when lymphangiography is contraindicated.
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May support 67Ga for intraabdominal lymphoma staging when lymphangiography contraindicated; leaves open its role in head and neck tumors.
The ability of 67Ga to detect clinically suspected head and neck tumors and lymphoma was evaluated. The radionuclide findings correlated with the pathological findings 65% of the time in tumors of the head and neck and were 87% accurate in lymphoma. Although the sensitivity of 67Ga testing was less in squamous-cell carcinoma of the head and neck than in lymphoma, specificity was comparable. Areas of normal 67Ga uptake in the salivary glands and upper mediastinum may obscure neoplasms in these areas. 67Ga added nothing to the staging of carcinoma of the head and neck but was of value in detecting intraabdominal lymphoma in patients in whom lymphangiography was contraindicated.
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Silberstein et al. (1974) studied this question.
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