Why the study?
Does optimizing vitamin D status improve outcomes in critically ill and injured patients?
Does optimizing vitamin D status improve outcomes in critically ill and injured patients?
Low vitamin D status is associated with significantly increased risks of myocardial infarction and mortality, highlighting the potential importance of optimizing vitamin D levels.
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Low vitamin D was associated with higher MI and mortality risk; leaves open whether repletion improves outcomes in trials.
In 2008, Giovanucci et al. [1] showed that men with low vitamin D levels suffered 2.42 times more myocardial infarctions than those with normal vitamin D status [1]. Alternatively, a sufficient amount of serum 25-hydroxyvitamin D3, [25(OH)D], appears to improve the risk of almost every disease of aging. Dobnig et al. [2] similarly demonstrated people with an inadequate vitamin D status have twice the likelihood of death over seven years [2,3].
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Omar K. Danner (2020) studied this question.
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