Why the study?
Intravascular papillary endothelial hyperplasia (IPEH) in the maxillary sinus is rare and can be difficult to distinguish from malignant tumors.
Intravascular papillary endothelial hyperplasia (IPEH) should be considered in the differential diagnosis of maxillary sinus masses that are difficult to distinguish from malignant tumors.
Maxillary sinus IPEH may mimic malignancy preoperatively; leaves open optimal noninvasive differentiation strategies for sinonasal masses.
Intravascular papillary endothelial hyperplasia （IPEH） is a benign lesion caused by the proliferation of vascular endothelial cells. We report an extremely rare case of IPEH derived from the maxillary sinus. A 52-year-old man visited our department with repeated right epistaxes from a month ago. Nasal endoscopy revealed discharge of blood from the right maxillary sinus ostium. CT and MRI showed a unilateral maxillary sinus mass with irregular edges on the maxillary sinus floor. It was difficult to determine preoperatively whether the mass was malignant or benign because of the lack of accessibility to the lesion for a biopsy. The maxillary sinus mass was resected by the Caldwell-Luc operation for diagnostic treatment. The histopathological diagnosis was IPEH. When IPEH occurs in the maxillary sinus, it may be difficult to distinguish from malignant tumors clinically and radiologically. Thus, it is worth knowing that IPEH is one of the differential diseases of maxillary sinus masses.
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Harada et al. (2022) studied this question.
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