Why the study?
What is the cumulative usage of desflurane required to maintain an end-expired concentration of 8% in patients undergoing elective spinal surgery?
What is the cumulative usage of desflurane required to maintain an end-expired concentration of 8% in patients undergoing elective spinal surgery?
The rate of desflurane uptake to maintain an 8% end-expired concentration shows a bi-exponential decline, with cumulative usage reaching 35.8 ml at 180 minutes.
May inform desflurane volume estimates in spinal surgery; leaves open generalizability and outcome impact.
The amount of desflurane required to maintain an end-expired concentration of 8% was measured in 30 ASA 1 and 2 patients undergoing elective spinal surgery. The anaesthetic was administered using a computer-controlled closed circle system. After an initial period during which the expired concentration of desflurane was stabilised (4 min) the rate of uptake showed a bi-exponential decline. Mean cumulative usage of desflurane was 10.1 ml of liquid at 30 min, 14.8 ml at 60 min, 25.4 ml at 120 min, 35.8 at 180 min.
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Walker et al. (1996) studied this question.
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