Population
Patients and mice chronically infected with Trypanosoma cruzi
Design
Review
Authors
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Absence of direct evidence cautions against autoimmunity-targeted therapies in Chagas' disease; leaves open parasite-driven mechanisms for study.
This review highlights the ongoing controversy and lack of definitive evidence supporting the autoimmunity hypothesis in the pathogenesis of Chagas' disease.
F Kierszenbaum (1999) studied this question.
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