Monodisperse chitosan microspheres with different structures are prepared and loaded with proteins, as exemplified in the figure. The different types of microspheres show different protein release profiles, which implies that that their properties can be adjusted to fit the needs of different therapeutic applications. The structural properties of the microspheres are varied by adjusting the surface charge, cavity size, and wall porosity.
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Wei et al. (2008) studied this question.
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