Epidemiology, Pathophysiology, and Prognostic Implications of Cystic Fibrosis–Related Diabetes

ystic fibrosis-related diabetes (CFRD) is the most common comorbidity in subjects with cystic fibrosis (CF). A consensus conference on CFRD was cosponsored by the Cystic Fibrosis Foundation (CFF), the American Diabetes Association (ADA), and the Pediatric Endocrine Society (PES) in September 2009. The committee's evidencebased recommendations for clinical management of CFRD are published in this issue of Diabetes Care. This review article describes the epidemiology, pathogenesis, and prognostic implications of CFRD.