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August 29, 2026Urology Case ReportsOpen Access

Upper tract urothelial carcinoma arising in a horseshoe kidney with ureteropelvic junction obstruction: a case report

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ACAhmed ChaabouniWEWafa ElleuchKCKays Chaker

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Overview

Case report reveals upper tract urothelial carcinoma in a giant hydronephrotic horseshoe kidney, highlighting the need to suspect malignancy in chronic ureteropelvic junction obstruction.

Key Points

  • To describe an exceptionally rare case of upper tract urothelial carcinoma developing in a horseshoe kidney complicated by longstanding ureteropelvic junction obstruction.
  • Clinical and computed tomography imaging evaluation of a 66-year-old male presenting with left flank pain and severe hydronephrosis.
  • Surgical intervention consisting of an open heminephroureterectomy followed by histopathological examination.
  • Computed tomography revealed massive hydronephrosis (50 × 46 × 28 cm) with contrast-enhancing urothelial wall thickening.
  • Histopathological analysis of the resected tissue confirmed upper tract urothelial carcinoma arising within the chronically obstructed renal moiety.

Cite This Study

Chaabouni et al. (2026) studied this question.

synapsesocial.com/papers/6a9299088e5d7d1fc0c10d03https://doi.org/10.1016/j.eucr.2026.103589
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