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August 29, 2026Neurorehabilitation

Autonomic Dysfunction After Pediatric Concussion: A Scoping Review

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Key result

Pediatric concussion frequently links to autonomic dysfunction anomalies despite variable findings across injury phases.

  • n=22

Why the study?

Despite concussions being common in children and adolescents, relatively little is known about the underlying pathophysiology of pediatric concussion, particularly autonomic dysfunction.

Population

Children and adolescents with concussion across 22 included studies

Design

Scoping review based on PRISMA-ScR guidelines

Authors

SRScott RamsayVancouver Coastal HealthHLHunter LloydVancouver Coastal HealthVKVioletta KobzevaUniversity of British Columbia

Discussion

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Implication

Autonomic dysregulation is associated with pediatric sport concussion; supports targeted autonomic assessment in recovery while highlighting need for standardized measures in trials.

Key Points

  • Synthesize the existing literature on autonomic dysfunction following pediatric concussion and identify the clinical measures used to evaluate autonomic function in youth.
  • Conducted a systematic search across six electronic databases following PRISMA-ScR guidelines.
  • Identified and synthesized 22 studies assessing autonomic nervous system function in children and adolescents after concussion.
  • Autonomic anomalies were documented in 15 of the 22 reviewed studies in pediatric populations, though findings and directions of effect varied across recovery phases.
  • Cardiovascular autonomic reflex testing in response to orthostatic stressors represented the most common evaluation method (n = 10), followed by aerobic exercise respiratory measures and ocular dynamics.

Study Design

Type

Systematic Review (n=22)

Structured PICO

P
Population
A scoping review of 22 studies evaluating autonomic dysfunction in children and adolescents following concussion.
O
Outcome
Autonomic dysfunction and procedures/measures testing autonomic functionsurrogate

This scoping review highlights that pediatric concussion is associated with varying degrees of autonomic dysfunction, though findings are mixed and require further prospective validation.

Cite This Study

Ramsay et al. (2026) conducted a systematic review in Pediatric concussion (n=22). Pediatric concussion was evaluated on Autonomic dysfunction anomalies. A scoping review of 22 studies found that 15 identified anomalies related to autonomic dysfunction in the concussed pediatric population, though findings varied across studies and injury phases.

synapsesocial.com/papers/6a92996e8e5d7d1fc0c11533https://doi.org/10.1177/10538135261479313
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-Term Influence of Concussion on Cardio-Autonomic Function in Adolescent Hockey Players2021 · 24 citations
  2. 2Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery2024 · 8 citations
  3. 3Cardiorespiratory Functioning in Youth with Persistent Post-Concussion Symptoms: A Pilot Study2021 · 7 citations
  4. 4The Clinical Utility of Assessing Orthostatic Intolerance in Adolescents with Sport-Related Concussion, a Retrospective Study2024 · 1 citations
  5. 5Interaction between Heart Rate and Heart Rate Variability2014 · 221 citations