Case report reveals Axenfeld–Rieger anomaly with secondary glaucoma in an adult male, highlighting the critical need for early clinical recognition and family screening.
Axenfeld–Rieger anomaly is a rare developmental disorder characterized by abnormalities of the iris, angle structures, and associated systemic features. Posterior embryotoxic and iris strands adherent to the anteriorly displaced Schwalbe’s line are the key features of this autosomal dominant condition. Iris abnormalities include hypoplasia, cecropia, and polyzoaria. We report a case of a 33-year-old male presenting with long-standing visual impairment, photophobia, and unilateral blindness due to prior trauma, with classical ocular and systemic manifestations suggestive of Axenfeld–Rieger anomaly. The case highlights the importance of early recognition, family screening, and glaucoma management in such patients.
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Khan et al. (2026) studied this question.
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