Key result
Coronary artery calcium scores (CACS) better predicted adverse outcomes, including MACE, death, and heart failure, than Q-risk scores in individuals with HIV.
Why the study?
HIV is associated with elevated coronary artery calcium scores, but risk factors beyond smoking and diabetes are not well established.
Does coronary artery calcium scoring (CACS) better predict adverse cardiovascular outcomes than Q-risk scores in individuals with HIV?
Cohort (n=779)
Does coronary artery calcium scoring (CACS) better predict adverse cardiovascular outcomes than Q-risk scores in individuals with HIV?
Coronary artery calcium scoring (CACS) improves cardiovascular risk prediction beyond traditional Q-risk scores in aging people with HIV.
In people without HIV, raised coronary artery calcium scores (CACS) are linked to increased cardiovascular risk. HIV is associated with elevated CACS, but risk factors beyond smoking and diabetes are not well established. Data on 779 individuals with HIV who underwent a CACS scans (median age 55) were collected. CACS better predicted adverse outcomes (e.g. major adverse cardiovascular events (MACE), death, heart failure) than Q-risk scores. Advanced imaging research may improve major cardiovascular risk prediction in people ageing with HIV.
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Varadarajan et al. (2026) conducted a cohort in HIV (n=779). Coronary artery calcium scores (CACS) vs. Q-risk scores was evaluated on Adverse outcomes (e.g. major adverse cardiovascular events (MACE), death, heart failure). Coronary artery calcium scores (CACS) better predicted adverse outcomes, including MACE, death, and heart failure, than Q-risk scores in individuals with HIV.
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