Case report describes delayed puberty, short stature, and central hypogonadism in 47,XYY syndrome, highlighting the necessity of comprehensive endocrine and genetic evaluation.
In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
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Javaid et al. (2026) studied this question.
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