We present results of a field trial carried on Telecom Italia EDFA-only legacy link with 0.3 dB/km average fiber attenuation. Single carrier 200G WDM DP-4QAM, DP-8QAM and DP-16QAM were successfully transmitted with system margin of 4.1 dB, 4.3 dB and 2.6 dB respectively
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Satoh et al. (1977) studied this question.
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