Key result
Emerging risk factors for cervical artery dissection include recent respiratory tract infection, migraine, hyperhomocysteinemia, and minor trauma such as chiropractic manipulation.
This review highlights emerging risk factors for cervical artery dissection, such as recent respiratory tract infection, migraine, and hyperhomocysteinemia, which require further investigation.
Should not yet change risk assessment or prevention; leaves open causal roles pending prospective validation.
Cervical artery dissection (CAD) represents an increasingly recognized cause of stroke and the most common cause of ischemic stroke in young adults. Many factors have been identified in association with CAD such as primary disease of arterial wall (fibrodysplasia) and other non-specific diseases related to CAD like Ehlers Danlos-syndrome IV, Marfan's syndrome, vessel tortuosity. Moreover, an underlying arteriopathy which could be in part genetically determined, has been suspected. The rule of emerging risk factors for CAD such as recent respiratory tract infection, migraine and hyperhomocysteinemia are still a matter of research. Other known risks factors for CAD are major head/neck trauma like chiropractic maneuver, coughing or hyperextension injury associated to car. We examined emerging risks factors for CAD detected in the last years, as CAD pathogenesis is still not completely understood and needs further investigations.
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Sara Micheli (2010) conducted a review in Cervical Artery Dissection. Emerging risk factors (e.g., infection, migraine, hyperhomocysteinemia, chiropractic manipulation) was evaluated. Emerging risk factors for cervical artery dissection include recent respiratory tract infection, migraine, hyperhomocysteinemia, and minor trauma such as chiropractic manipulation.
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